26 août 2012

EGF of the distribution and expression

      EGF of angiogenesis is thought to play a key role, in part because the receptors and raised VEGFmRNA expression and regulation angiogenesis. Studies have pointed out that EGF and EGF-R continued combination, it can guide EGF-R into degradation. We study found that in normal tissue and high oxygen lung damage vascular endothelial cells are visible EGFR strong positive expression, blood vessels in the wall of the cable shape distribution, identical with those reported in literature. Our experimental... [Lire la suite]
Posté par Hense007 à 16:35 - Commentaires [0] - Permalien [#]

22 août 2012

B-EGFmRNA and protein expression

      B-EGFmRNA and protein expression,in pregnancy d1,the expression of the HB-EGF is higher,the main distribution in endometrial cavity epithelial and glandular epithelium,pregnancy d2~3,the expression of the HB-EGF is very small,at the blastocyst before and after implantation,the expression of the HB-EGF is higher,and a regional distribution,mainly distributed in the lining of the uterus is film side cavity epithelial inside,and in between two blastocysts endometrial cavity epithelial expressed in the... [Lire la suite]
Posté par Hense007 à 17:22 - Commentaires [0] - Permalien [#]
20 août 2012

Heparin-binding nature of EGF-like growth factor ( HB -EGF ) Profile

      HB-EGF is a member of the EGF family of recently discovered one of the first growth factor with heparin affinity chromatography to separate from the macrophage-like U-937 cell-conditioned medium composed of 208 amino acid residues molecular weight of 20 ~ 22kD.HB-EGF gene is located on chromosome 5 and mouse chromosome No.18.HB-EGF expression in many organizations,including lung,heart,kidney,testis and skin.HB-EGF with cell surface heparin sulfate proteoglycan ( HSPG) and EGFR can stimulate cell... [Lire la suite]
Posté par Hense007 à 17:20 - Commentaires [0] - Permalien [#]